Ion Chromatography–Mass Spectrometry (IC-MS) offers powerful analytical capabilities, but optimal sensitivity and long-term performance require thoughtful system setup. This webinar covers practical strategies for optimizing IC-MS, focusing on the components and decisions that most strongly impact routine analysis.

Topics that will be covered include:

• The importance of high-quality eluent
• How the suppressor can affect instrument lifetime
• How to select the right mass spectrometer for your sensitivity needs
• Eluent management strategies to minimize stress on the MS, avoid contamination, and maintain stable performance

Mastering Charged Aerosol Detection (CAD): Understand, Optimize and Troubleshoot

This technical webinar provides an in-depth overview of Charged Aerosol Detection (CAD) and its application in modern liquid chromatography. The session presents the fundamental principles and underlying technology of the Charged Aerosol Detector, delivered by our experts.

Learning Points:

• In-depth technical understanding of CAD technology and critical system parameters
• Practical approaches for optimizing CAD methods based on mobile phase composition and application requirements
• Structured troubleshooting strategies for common CAD performance issues

Why HPLC-CAD is ideal for quality assurance of APIs and excipients

The gold standard of quality assessment of drugs is nowadays an HPLC using a reversed-phase (RP) column chromatography and aqueous buffers, acetonitrile, and/or methanol as mobile phase, combined with a UV detector. 

Key learning and takeaways include:

• Explore on the critical yet increasingly complex challenge of impurity profiling of APIs and excipients in pharmaceutical analysis
• Review on enhancement of sensitivity in detection to uncover low-level impurities
• Discover examples for quality assurance by HPLC-CAD analysis

Chromeleon Admin Console II: System management and automation